5 beste Stellen als phd biology in heidelberg, bw – aktuell auf Personalsuche

PhD/Postdoc position in computational biology to elucidate NR2F1 dosage dependent regulatory networks in health and disease (m/f/d)
Universitätsklinikum Heidelberg —Heidelberg
- Vollzeit
- Doktorat
- Datenanalyse
- Python
12 Tage
PhD – Position (m/f/d)
Universitätsklinikum Heidelberg —Heidelberg
- Teilzeit
- Doktorat
- Krankenhaus
- Master
PhD position (m/w/d)
Universitätsklinikum Heidelberg —Heidelberg
- Teilzeit
- Master
Postdoctoral Researcher – Translational Oral Biofilm Research (m/f/d)
Universitätsklinikum Heidelberg —Heidelberg
- Vollzeit
- Doktorat
- Datenanalyse
- Forschungserfahrung
- Flexible Arbeitszeiten
Postdoctoral Researcher (m/f/d) B Cell Immunology & Single-Cell Technologies (Team TAP)
BioMed X AG —Heidelberg
- Doktorat
- Datenanalyse
- Python
2 Tage

More jobs to discover

Find similar jobs that you might be interested in.

PhD – Position (m/f/d)
Universitätsklinikum Heidelberg —Heidelberg
Claus Schmitt is seeking talented and motivated researchers to work as a PhD student on a DFG-funded grant (Therapeutic potential of dipeptides in diabetic…
PhD/Postdoc position in computational biology to elucidate NR2F1 dosage dependent regulatory networks in health and disease (m/f/d)
Universitätsklinikum Heidelberg —Heidelberg
By integrating time-resolved bulk (RNA-seq, ATAC-seq, ChIP-seq, Hi-C) obtained from neuronal lineages cultured in 2D cells and single-cell multi-omics (scRNA-…
12 Tage

Ich möchte aktuelle Job-E-Mails für Stellen als phd biology in heidelberg, bw erhalten

Wenn Sie sich bei Ihrem Konto anmelden, stimmen Sie den Nutzungsbedingungen, den Richtlinien zur Verwendung von Cookies sowie der Datenschutzerklärung von SimplyHired zu.

Weitere Job-Standorte erkunden

phd biology jobs near heidelberg, bw

Jobs als Postdoctoral Researcher in Tübingen

Jobs als Researcher in Potsdam

Jobs als Postdoctoral Researcher in Bremen

Jobs als Ps Team in Walluf

Jobs als Adesta Team in Darmstadt

PhD/Postdoc position in computational biology to elucidate NR2F1 dosage dependent regulatory networks in health and disease (m/f/d)

Universitätsklinikum Heidelberg -
Heidelberg

Jetzt bewerben

Details zur Stelle

Vollzeit
vor 12 Tagen

Leistungen

Jobticket

Qualifikationen

Biologie
Doktorat
R
Datenanalyse
C
Python
Shell Scripting

Vollständige Stellenbeschreibung

Stellenanzeige merken

We are looking for an enthusiastic Postdoc/PhD to join our research group to study gene regulation in neurodevelopment with a focus on how NR2F1 dosage shapes the specification of neuronal lineages and the formation of cortical circuits.

NR2F1 is a key transcription factor controlling embryonic neuronal development. Mutations and deletions of NR2F1 lead to Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Using neuronal cells derived from CRISPR/Cas9 engineered human induced pluripotent stem cells (hiPSC) we model distinct NR2F1 dosages to study their effects across neuronal differentiation. By integrating time-resolved bulk (RNA-seq, ATAC-seq, ChIP-seq, Hi-C) obtained from neuronal lineages cultured in 2D cells and single-cell multi-omics (scRNA-seq, scATAC-seq, Multiome) data generated in 3D forebrain dorsal organoids, we aim to map regulatory networks sensitive to NR2F1 expression levels.

Our group studies the fundamental principles of embryonic neuronal development by combining genomics, gene editing, and bioinformatics. We offer an international, dynamic, and supportive research environment that fosters creativity and career growth. The AG Laugsch is embedded within Heidelberg’s excellent computational biology network, fostering close collaborations with experts like Carl Herrmann (Institute of Pharmacy and Molecular Biotechnology), and Julio Saez-Rodriguez (Systems Biomedicine, Institute of Computational Biomedicine. If you are a curiosity-driven researcher who enjoys interdisciplinary teamwork and tackling complex biological questions through data, we would be delighted to hear from you. The application must include your motivation, a brief statement of your scientific interests, contact details from three references, curriculum vitae, separated publication list, and relevant certificates.

https://www.klinikum.uni-heidelberg.de/humangenetik/forschung/ag-laugsch/

Literature:

https://doi.org/10.64898/2026.06.25.734423

https://doi.org/10.64898/2026.05.01.722223

doi: 10.1016/j.stem.2019.03.004.

Job-ID: V000015909
Einsatzgebiet: Institut für Humangenetik
Einsatzort: Heidelberg
Tätigkeitsbereich: Wissenschaft und Lehre
Anstellungsart: Vollzeit
Veröffentlicht: 13.07.2026
Befristung:Befristet (3 Jahre)
Vertrag:TV-L

Ihre Aufgaben

Establish computational pipelines for the analysis and integration of single-cell multi-omics data (scRNA-seq, scATAC-seq, Multiome) to reconstruct gene regulatory networks in 3D forebrain dorsal organoids to determine pathophysiological consequences of aberrant NR2F1 dosage
Design and build an interactive, open-access web platform for visualization and usage of multi-omics datasets
Integrate newly generated data with in-house and publicly available datasets to interpret results in a robust biological context
Ensure reproducibility, data management, and documentation of computational workflows in high-performance computing environments
Collaborate closely with experts in computational biology across the university and affiliated institutes, as well as with experimental researchers (wet lab) in the AG Laugsch, to support accurate data interpretation and integration
Maintain clear documentation of analyses and computational workflows on eLab and provide regular progress reports and updates
Actively participate in regular journal clubs and institute meetings. Present findings at lab meetings and international conferences and contribute to manuscripts and grant applications.

Your Profile

Strong background in bioinformatics or computational biology
Practical experience with omics data pre-processing, pipeline development, and high-performance computing
Proficiency in R or Python, and shell scripting
Interest in gene regulation and developmental biology
Optional previous experience with epigenomic data analysis or gene regulatory network inference
Ability to work independently and collaboratively in a multidisciplinary environment
Excellent written and spoken English skills

What we offer

Collectively agreed remuneration TV-L E13, attractive company pension scheme (VBL)
30 days vacation
Sustainable travel: job ticket
Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
Wide range of health, prevention and sports offers
Possibility to publish scientifically is offered and supported
Regular team meetings
Possibility of doctorate

Kontakt & Bewerbung

For further information please contact Dr. rer. nat. Magdalena Laugsch via e-mail.

Interested?

Applications will be accepted until 31.08.2026 online.

Institut für Humangenetik
Dr. rer. nat. Magdalena Laugsch, Group Leader
Im Neuenheimer Feld 366
69120 Heidelberg
+49 6221 56-39128
[email protected]

Hinweis: Das UKHD unterliegt den Bestimmungen des Infektionsschutzgesetzes. Daher ist für alle am UKHD beschäftigten Personen ein gültiger Masern-Immunitätsnachweis notwendig.

Das UKHD lebt Vielfalt und schätzt die Diversität.

Unabhängig von Alter, Geschlecht, sexueller Identität, Behinderung, Herkunft oder Religion bieten wir allen die gleichen Chancen. Wenn ein Geschlecht in einem bestimmten Bereich unterrepräsentiert ist, legen wir besonderen Wert darauf, diesem Ungleichgewicht entgegenzuwirken. Bei gleicher Eignung, Befähigung und fachlicher Leistung geben wir Menschen mit Schwerbehinderung Vorrang bei der Berücksichtigung für offene Stellen.

Jetzt bewerben

Erweiterte Suche

phd biology Jobs in heidelberg, bw

PhD/Postdoc position in computational biology to elucidate NR2F1 dosage dependent regulatory networks in health and disease (m/f/d)

PhD – Position (m/f/d)

PhD position (m/w/d)

Postdoctoral Researcher – Translational Oral Biofilm Research (m/f/d)

Postdoctoral Researcher (m/f/d) B Cell Immunology & Single-Cell Technologies (Team TAP)

More jobs to discover

Ich möchte aktuelle Job-E-Mails für Stellen als phd biology in heidelberg, bw erhalten

Weitere Job-Standorte erkunden

Ihre Aufgaben

Your Profile

What we offer

Kontakt & Bewerbung

Tools für Jobsuchende

Arbeitgebertools

Durchsuchen

Bleiben Sie in Kontakt