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Postdoctoral position: Gene expression regulation (f/m/x) Uhlirova Lab/Institute for Genetics/CECAD

Universität zu Köln -
Köln

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Biologie
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Postdoctoral position: Gene expression regulation (f/m/x)
Uhlirova Lab/Institute for Genetics/CECAD

We are one of the largest and oldest universities in Europe and one of the most important employers in our region. Our broad range of subjects, the dynamic development of our main research areas and our central location in Cologne make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration.

The Uhlirova lab ( www.uni-koeln.de/inter-fak/cecad/uhlirova/ ) explores how stress-inducible signaling pathways control gene expression and influence tissue homeostasis and longevity. To tackle these questions, we combine the power of functional genetics in Drosophila and mouse models with cutting-edge molecular and cell biology, multi-omics approaches, advanced microscopy, and bioinformatics. We are looking for a highly motivated and curious postdoctoral candidate (f/m/x) to join our dynamic team. You will have the opportunity to lead your own project, contribute to collaborative research, and develop skills at the interface of genetics, molecular and cell biology, and systems-level analysis.

YOUR TASKS

To study the crosstalk between transcription and pre-mRNA splicing under physiological, stress, and disease conditions
To investigate mechanisms underlying spliceosome assembly and functional plasticity
To uncover what renders different transcripts, cells, and tissues sensitive to aberrant splicing

YOUR PROFILE

Completed doctoral degree in Biology / Biochemistry/ Biophysics or related areas of Life Sciences
Motivation, curiosity and creativity, and a strong ability to solve problems through critical analytical thinking
Strong background in genetics, molecular and cell biology is essential
Proven ability to carry out an independent scientific project and unwavering commitment to high-quality research
Hands-on experience in working with model organisms, preferably Drosophila and/or mouse and in vitro systems
Excellent communication skills, fluency in spoken and written English

DESIRED ASSETS

Experience in multi-omics research projects and data analysis
Familiarity with iPSC and / or organoid models
Expertise in computational modeling of protein–RNA and protein–protein interactions
Experience in quantitative image analysis and attention to detail

WE OFFER

Interactive and international team with access to the state-of -the-art research facilities
A diverse working environment with equal opportunities
Support in balancing work and family life
Extensive advanced training opportunities
Occupational health management offers

The University of Cologne promotes equal opportunities and diversity. Women will be considered preferentially in accordance with the Equal Opportunities Act of North Rhine-Westphalia (Landesgleichstellungsgesetz – LGG NRW). We also expressly welcome applications from all suitable candidates regardless of their gender, nationality, ethnic and social origin, religion, disability, age, sexual orientation and identity.

The position is available from 1 October 2026 on a full-time basis (39,83 hours per week). It is limited for two years until 30 September 2028. If the applicant meets the relevant wage requirements and personal qualifications, the salary is based on remuneration group 13 TV-L of the pay scale for the German public sector.

Please apply online with proof of the required qualifications and the following documents:

A cover letter describing your motivation to join our research group and information on your career achievements (1 page max.)
Academic Curriculum Vitae (without a photo), including your publication list and contact information for three references
Copies of your degree and qualification certificate

Please apply at: https://jobportal.uni-koeln.de . The reference number is Wiss2603-13. The application deadline is 15 June 2026.

For further inquiries, please contact Professor Mirka Uhlirova/Dr Esther Wollert at ( [email protected] e) and take a look at our FAQs.

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