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PhD candidate (f/m/x) in Systems Medicine

Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE) -
Bonn

Jetzt bewerben

Details zur Stelle

Vollzeit
vor 4 Tagen

Leistungen

Flexible Arbeitszeiten

Qualifikationen

Biologie
Molekularbiologie
Master

Vollständige Stellenbeschreibung

The German Center for Neurodegenerative Diseases (DZNE) is a globally leading, internationally oriented research institution dedicated to discovering new approaches for the prevention and treatment of neurodegenerative diseases.

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Your role in detail

The research area Systems Medicine (DZNE Bonn site) is recruiting a PhD candidate in the field of Molecular and Translational immunaging. We are looking for a highly motivated PhD candidate to join our dynamic team and work at the forefront of omics technologies, organoid, animal models, and computational biology. This position offers a unique opportunity to contribute to the understanding of the clinical impact of chronic PFAS exposure worldwide and to develop a blueprint for studying the immunotoxicity of other environmental pollutants.

In this role you will

design and carry out single‑cell multi‑omics and high‑dimensional cytometry experiments
develop and maintain organoid and animal model systems, and perform comprehensive data analysis using modern computational pipelines
investigate PFAS‑driven changes in the immune system
identify molecular pathways involved, and explore potential intervention strategies
Your work will be conducted in close collaboration with experts in data and information sciences, immunology, and epidemiology, fostering a truly interdisciplinary environment
work with fully established genomics, bioinformatics and wet-lab facilities and modular high-performance computing resources
benefit from a membership in one of our graduate school programs

Your profile in cutting edge research

Master or equivalent in molecular biology, immunology, bioinformatics, systems biology, or comparable topics
Strong research background in immunology, cell biology, and genomics or transcriptomics
Strong interest in omics technologies and computational analysis
Practical experience in multi-color flow cytometry, molecular and cell biology, and transcriptomics is of advantage
Experience with cell culture, flow cytometry, or animal models is highly desirable, as is proficiency in programming languages such as R or Python for high‑dimensional data analysis
Practical experience in working with mice as animal models is of advantage.
Practical knowledge of data analysis and machine learning using R or Python is of advantage
Very good English proficiency
Enthusiastic and collaborative work attitude
Ability to work independently as well as in a team
Excellent communication skills, a collaborative mindset, and a passion for addressing impactful questions in systems medicine are essential

Your role in cutting edge research

The Systems Medicine group at the DZNE Bonn site is a diverse, international team that investigates how chronic inflammation, aging, exposome, and neurodegenerative diseases intersect with the immune system. Our current research focuses on per‑ and polyfluoroalkyl substances (PFAS), ubiquitous environmental contaminants, and aims to uncover the molecular mechanisms by which PFAS exposure alters immune function, especially in older individuals and in the context of non‑communicable diseases.

If you are eager to contribute to transformative research that bridges environmental exposure and immune health, we encourage you to apply.

For more general information, please also visit the website of Systems Medicine.
https://www.dzne.de/en/research/research-areas/systems-medicine/

Your benefits

Innovation and internationality:
A forward-looking infrastructure, modern laboratory and office equipment, software tools and the opportunity for international exchange with your colleagues from 65 nations
Focus on Development:
Training programmes tailored to your individual needs and annual HR-development meetings for concrete prospects and potential development
Health promotion:
Through our extensive range of company health programmes, in cooperation with Sozialwerk.Bund
Remuneration and conditions according to TVöD-Bund:
Including annual special payment, capital-forming benefits and VBL supplementary pension scheme
Work-life balance:
We reconcile work and private life with flexible working hours, 30 days' holiday (On top free on Christmas Eve and New Year's Eve) and subsidised job/ Germany ticket options
Family-conscious corporate culture:
Because we know that family is important, we support you with our family service

Your application

Excellence in research thrives on diverse perspectives and experiences. We stand for a respectful and open culture. We promote equal opportunities, remove barriers, and welcome applications from people across all dimensions of diversity. We particularly welcome applications from people with disabilities.

If you have any questions regarding the advertised position, please contact Dr. Lorenzo Bonaguro

Jill Lewandowski

Team HR Recruiting
+49 228 43302 147

Jetzt bewerben

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