Postdoc - Chemistry Innovations for Oligonucleotide Therapeutics (m/f/d)
Grünenthal —Aachen
- Vollzeit
- Doktorat
- Kommunikationsfähigkeit
- Python
2 Std.
Senior Data Scientist (m/w/d)
INC Innovation Center GmbH —Aachen
- Azure
- Doktorat
- Informatik
- Weiterbildungsprogramme
- Flexible Arbeitszeiten
Direkt bewerben
IT-Allrounder (m/w/d/x) – Systemadministration & Infrastruktur
crop.zone GmbH —Aachen
- Vollzeit
- CRM-Software
- Azure
- Englisch
Direkt bewerben
Praktikanten (m/w/d) – Instrumentelle Qualitätsbewertung
HEAD acoustics GmbH —Herzogenrath
- Informatik
- Elektrotechnik
- Python
Wissenschaftlicher/r Mitarbeiter/in (w/m/d) für das Forschungskolleg „Wohlbefinden von Menschen in Innenräumen” (Heinz Trox-Stiftung): Schwerpunkt Kindertagesstätten & Schulen
RWTH Aachen University —Aachen
- Per E-Mail
- Englisch
- Master
- Python
- Weiterbildungsprogramme
Wissenschaftliche/-r Mitarbeiter/-in (w/m/d) in Human Factors mit Promotionsabsicht
Universitätsklinikum Aachen AöR —Aachen
- Online-Bewerbung
- Englisch
- Master
- Scripting
- Weiterbildungsprogramme
- Empfehlungsprogramm
Direkt bewerben
13 Tage
Wissenschaftliche/r Mitarbeiter/in (w/m/d) für das Forschungskolleg „Wohlbefinden von Menschen in Innenräumen” (Heinz Trox-Stiftung): Schwerpunkt Reha- und (Kurzzeit-)Pflegeeinrichtungen
RWTH Aachen University —Aachen
- Per E-Mail
- Englisch
- Master
- Python
- Weiterbildungsprogramme
Wissenschaftliche/-r Mitarbeiter/-in -Post Doc- (w/m/d)
Universitätsklinikum Aachen AöR —Aachen
- Teilzeit
- Doktorat
- Datenanalyse
- Psychologie
- Empfehlungsprogramm
Direkt bewerben
Ausbildung/Duales Studium - Mathematisch-technischer Softwareentwickler (m/w/d)
Ehrhardt + Partner Group (EPG) —Aachen
- Vollzeit
- Englisch
- Hochschulreife
- C++
- Flexible Arbeitszeiten
Direkt bewerben
Senior System Integration / Build Engineer (m/w/d)
Nexburg GmbH —Aachen
- Vollzeit
- Informatik
- DevOps
- Englisch
- Homeoffice-Möglichkeit
- Flexible Arbeitszeiten
Direkt bewerben

Discover related jobs

Based on your search for python jobs.

Software developer (Web/Internet of Things)
Team Tachyon e.V. —Aachen
As a Software Developer you will design and develop the GUIs for our projects such as electrical vehicles, robotics and industrial machines.
Studentische/r Mitarbeiter/in Web Development (w/m/d)
IconPro GmbH —Aachen
Du gestaltest und optimierst benutzerfreundliche und responsive Benutzeroberflächen. Du arbeitest in einem agilen Team mit Back-End-Entwicklern für eine…

Ich möchte aktuelle Job-E-Mails für Stellen als python in aachen erhalten

Wenn Sie sich bei Ihrem Konto anmelden, stimmen Sie den Nutzungsbedingungen, den Richtlinien zur Verwendung von Cookies sowie der Datenschutzerklärung von SimplyHired zu.

Weitere Job-Standorte erkunden

python jobs near aachen

Jobs als Wissenschaftliche Mitarbeiter in Aachen

Jobs als Praktikum in Herzogenrath

Jobs als Wissenschaftlicher Mitarbeiter Kanzlei in Frankfurt Am Main

Jobs als Wissenschaftliche Mitarbeiter in Recklinghausen

Jobs als Wissenschaftliche Mitarbeiter in Schwetzingen

Jobs als Wissenschaftliche Mitarbeiter in Offenbach

Jobs als Wissenschaftliche Mitarbeiter in Herten

Jobs als Freie Mitarbeiter in München

Jobs als Jura, Wissenschaftlicher Mitarbeiter in Home Office

Jobs als Kaufmännischer Mitarbeiter in Bitterfeld Wolfen

Jobs als Mitarbeiter Empfang Minijob in Berlin

Jobs als Tankstelle Mitarbeiter in Rastatt

Jobs als Wissenschaftliche Mitarbeiter Psychologie in Nordrhein Westfalen

Jobs als Wissenschaftliche Mitarbeiter in Euskirchen

Jobs als Frühstücks Mitarbeiter in Berlin

Jobs als Wissenschaftliche Mitarbeiter in Jena

Jobs als Wissenschaftliche Mitarbeiter in Regensburg

Jobs als Wissenschaftliche Mitarbeiter in Berlin

Jobs als Softwareentwickler in Nordrhein Westfalen

Jobs als Senior System Engineer in München

Postdoc - Chemistry Innovations for Oligonucleotide Therapeutics (m/f/d)

Grünenthal -
Aachen

Jetzt bewerben

Details zur Stelle

Vollzeit
vor 2 Stunden

Qualifikationen

Biologie
Backbone.js
Doktorat
Kommunikationsfähigkeit
Python

Vollständige Stellenbeschreibung

Postdoc - Chemistry Innovations for Oligonucleotide Therapeutics (m/f/d)

Country: Germany

City: Aachen

Department: Research & Development

Job ID: 45302

Graduate | Temporary | Full-time | On-Site

If you’re passionate about changing lives for the better, this is the opportunity you’ve been waiting for. In Research & Development, we’re continuously exploring innovative new treatment options to make a stronger, more positive impact on the lives of the patients we serve. You’ll work with talented colleagues in a state-of-the-art Research & Development environment, developing innovative medicines that change the life of patients for the better and help us make progress towards our vision of a world free of pain. Join us today and discover the difference you can make.

Our uniquely integrated approach brings together leading capabilities in small molecule and oligonucleotide chemistry, enabling powerful cross-talk between modalities and unlocking novel therapeutic opportunities. Within our Chemistry, Discovery Biology, and Genetic Medicine groups, we are pioneering RNA-based therapeutics and next-generation delivery technologies, with a strong focus on overcoming key challenges in siRNA and ASO delivery.

As part of our 24-month Postdoctoral Programme, with potential extension to 36 months, we are looking for you – A proactive and innovative thinker, a team player and creative problem-solver, eager to challenge conventions and make a real impact. You will work on cutting-edge projects, build a strong scientific network, and benefit from dedicated mentoring, leadership coaching, and tailored development opportunities to accelerate your personal and professional growth.

What the job looks like

In this role, you will operate at the interface of chemistry and biology, partnering closely with a biochemistry and biophysics-focused postdoctoral scientist to build a center of excellence in oligonucleotide delivery. You will be embedded across Grünenthal’s Chemistry, Discovery Biology, and Genetic Medicine groups, working in a uniquely integrated environment that enables rapid translation from chemical innovation to biological impact.

Leveraging cutting-edge internal synthesis capabilities, you will explore and advance a broad range of design strategies, including backbone, sugar, nucleotide, linker, and conjugate modifications. In addition, you will engage with external partners across small molecule, peptide, and antibody technologies to expand delivery modalities and unlock new therapeutic opportunities.

Your Key Responsibilities:

Hands-on Oligonucleotide Chemistry (Lab-Based): Design and synthesize novel siRNA/ASO constructs using advanced backbone modifications, custom monomers, and innovative conjugation strategies to enhance delivery and cellular uptake.
Next-Generation Delivery Design: Develop and optimize targeted conjugates (e.g., lipid-, peptide-, and receptor-based) to improve tissue specificity and intracellular trafficking.
Collaborative Innovation: Partner closely with biochemistry and biophysics experts in iterative design–make–test cycles to translate chemistry into biological impact.
Embedded in a Distinguished Scientific Network: Contribute within a leading chemistry organization and Genetic Medicine group, collaborating with internationally recognized experts across disciplines.
Translational Impact & Scientific Excellence: Drive data interpretation, communicate results in high-impact publications, and help shape Grünenthal’s genetic medicine strategy.

What you'll bring to the table

To thrive in this role, you should have:

We are seeking a highly motivated Postdoctoral Scientist with expertise in oligonucleotide chemistry to help shape the next generation of siRNA and ASO therapeutics with improved activity, stability, and delivery.
You hold a Ph.D. in Organic Chemistry, Chemical Biology, or a related field, with strong hands-on experience in oligonucleotide synthesis. You bring deep expertise in phosphoramidite chemistry, as well as in the design of linkers and conjugates at both terminal and internal oligonucleotide positions.
You have a solid background in bioconjugation chemistry, including the development of siRNA/ASO conjugates (e.g., via click chemistry and related approaches), and are proficient in advanced analytical techniques such as HPLC and mass spectrometry.
You thrive in a collaborative, cross-disciplinary environment, working seamlessly with biology-focused scientists to translate chemical innovation into functional delivery solutions through iterative design–make–test cycles.
Personally, you are curious, proactive, and open-minded, with a strong drive to learn and explore new technologies. You are a self-motivated team player with excellent communication skills and fluency in English.
Experience with programming (e.g., Python) for oligonucleotide sequence analysis is an advantage, as is exposure to international and multicultural working environments.

Come on board & look forward to:

Attractive compensation and extensive social benefits
30 vacation days + bridging days
Wide range of company benefits e.g. health initiatives & sports activities

About Grünenthal

Grünenthal is a global leader in pain management and related diseases. As a science-based, privately-owned pharmaceutical company, we have a long track record of bringing innovative treatments and state-of-the-art technologies to patients worldwide. Our purpose is to change lives for the better – and innovation is our passion. We are focussing all of our activities and efforts on working towards our vision of a world free of pain.

Grünenthal is headquartered in Aachen, Germany, and has affiliates in 28 countries across Europe, Latin America and the US. Our products are available in more than 100 countries. In 2024, Grünenthal employed around 4,300 people and achieved sales of € 1.8 billion.

1d9a1869/3aec922a-b6e4-4999-8ee8-3.jpg

Your HR contact:

Anke Harmuth

1d9a1869/4c1b1cc3-b9e5-4add-8140-4.jpg

Meet our teams
Website: www.grunenthal.com
LinkedIn: Grunenthal Group
Instagram: @grunenthal

Jetzt bewerben

Erweiterte Suche

python Jobs in aachen

Postdoc - Chemistry Innovations for Oligonucleotide Therapeutics (m/f/d)

Senior Data Scientist (m/w/d)

IT-Allrounder (m/w/d/x) – Systemadministration & Infrastruktur

Praktikanten (m/w/d) – Instrumentelle Qualitätsbewertung

Wissenschaftlicher/r Mitarbeiter/in (w/m/d) für das Forschungskolleg „Wohlbefinden von Menschen in Innenräumen” (Heinz Trox-Stiftung): Schwerpunkt Kindertagesstätten & Schulen

Wissenschaftliche/-r Mitarbeiter/-in (w/m/d) in Human Factors mit Promotionsabsicht

Wissenschaftliche/r Mitarbeiter/in (w/m/d) für das Forschungskolleg „Wohlbefinden von Menschen in Innenräumen” (Heinz Trox-Stiftung): Schwerpunkt Reha- und (Kurzzeit-)Pflegeeinrichtungen

Wissenschaftliche/-r Mitarbeiter/-in -Post Doc- (w/m/d)

Ausbildung/Duales Studium - Mathematisch-technischer Softwareentwickler (m/w/d)

Senior System Integration / Build Engineer (m/w/d)

Discover related jobs

Ich möchte aktuelle Job-E-Mails für Stellen als python in aachen erhalten

Related Searches

Weitere Job-Standorte erkunden

Postdoc - Chemistry Innovations for Oligonucleotide Therapeutics (m/f/d)

About Grünenthal

Tools für Jobsuchende

Arbeitgebertools

Durchsuchen

Bleiben Sie in Kontakt