We are one of the largest and oldest universities in Europe and one of the most important employers in our region.
Our broad range of subjects, the dynamic development of our main research areas and our central location in Cologne
make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in
science, technology, and administration.
The Uhlirova lab (www.uni-koeln.de/inter-fak/cecad/
uhlirova/) explores how stress-inducible signaling pathways
control gene expression and influence tissue homeosta-
sis and longevity. To tackle these questions, we combine
the power of functional genetics in Drosophila and mouse
models with cutting-edge molecular and cell biology, mul-
ti-omics approaches, advanced microscopy, and bioinfor-
matics. We are looking for a highly motivated and curious
doctoral candidate (f/m/x) to join our dynamic team. You will
have the opportunity to lead your own project, contribute
to collaborative research, and develop skills at the interface
of genetics, molecular and cell biology, and systems-level
analysis.
YOUR TASKS
» To study the crosstalk between transcription and
pre-mRNA splicing under physiological, stress, and
disease conditions
» To investigate mechanisms underlying spliceosome
assembly and functional plasticity
» To uncover what renders different transcripts, cells,
and tissues sensitive to aberrant splicing
» To investigate how spliceosome malfunction
contributes to loss of tissue homeostasis, premature
aging and diseases
YOUR PROFILE
» Completed Master‘s degree or equivalent in Biology /
Biochemistry/ Biophysics or related areas of Life
Sciences
» Strong background in genetics, molecular and cell
biology is essential
» Motivation, curiosity and creativity, and a strong ability
to solve problems through critical analytical thinking
» Proven ability to carry out an independent scientific
project and unwavering commitment to high-quality
research
» Hands-on experience in working with model organisms,
preferably Drosophila and/or mouse and cell culture
systems
» Excellent communication skills, fluency in spoken and
written English
» Strong commitment to collaboration and teamwork
DESIRED ASSETS
» Hands-on experience in multi-omics research projects
and data analysis
» Experience with protein purification and biomolecular
interaction assays
» Interest in computational modeling of biomolecular
interactions
» Experience in quantitative image analysis and attention
to detail
» Strong organizational and thorough documentation skills
WE OFFER
» Interactive and international team with access
to state-of-the-art research facilities
» A diverse working environment with equal opportunities
» Support in balancing work and family life
» Extensive advanced training opportunities
» Occupational health management offers
» Flexible working time models
The University of Cologne promotes equal opportunities and
diversity. Women will be considered preferentially in accord-
ance with the Equal Opportunities Act of North Rhine-West-
phalia (Landesgleichstellungsgesetz – LGG NRW). We also
expressly welcome applications from all suitable candidates
regardless of their gender, nationality, ethnic and social
origin, religion, disability, age, sexual orientation and identity.
The position is available from immediately on a part-time
basis (25,89 hours per week).The position is to be filled
for three years. If the applicant meets the relevant wage
requirements and personal qualifications, the salary is
based on remuneration group 13 TV-L of the pay scale for
the German public sector.
Please apply online without a photo at
https://jobportal.uni-koeln.de with proof of the required
qualifications and the following documents:
» A cover letter describing your motivation to join our
research group and information on your career
achievements (1 page max.)
» Academic Curriculum Vitae, including your publication
list and contact information for three references
» Copies of your degree and qualification certificate
The reference number is Wiss2608-13. The application
deadline is 27 September 2026.
For further inquiries, please contact Dr Esther Wollert
([email protected]) and take a look at our FAQs.
Doctoral Position: Gene Expression Regulation (f/m/x)
Faculty of Mathematics and Natural Sciences
Uhlirova Lab | Institute for Genetics | CECAD
