The main research interest of our group lies in the reaction of metabolic tissues to various environmental factors, such as temperature challenges and food constituents. We recently identified the Aryl Hydrocarbon Receptor Repressor (AhRR) as a pivotal regulator of thermogenesis and metabolic processes (Graelmann, FJ et al, Mol Metab 2024). In this project, the candidate will investigate how environmental factors influence the plasticity of thermogenic adipose tissues, including pathways controlling preadipocytes and endothelial cells (Reverte-Salisa, L et al, Nat Cell Biol 2024). To investigate these processes the candidate will use mouse models, classical in vitro methods but also cutting-edge technologies, such as flow cytometry, metabolomics, and snRNA sequencing.
The position is available within the Transregional Collaborative Research Centre (TRR) 333 “BATenergy: Brown and Beige Fat - Organ Crosstalk, Signaling and Energetics” funded by the Deutsche Forschungsgemeinschaft (DFG). For further information please refer to https://www.limes-institut-bonn.de/en/research/research-departments/unit-2/foerster-lab/foerster-lab-home/ and https://www.trr333.uni-bonn.de/
