Positron emission tomography is conventionally performed with one radiotracer at a time. Yet tumour biology is not one-dimensional: metabolism, receptor expression and immune-related pathways provide complementary information, while separate examinations on different days increase burden and complicate direct biological comparison.
This doctoral project will exploit the exceptional sensitivity of long-axial field-of-view (LAFOV) PET to make clinically feasible, same-session multi-tracer imaging a reality. The goal is to derive complementary quantitative biomarkers from a single patient visit - with reduced injected activity, improved temporal correspondence and direct clinical relevance.
You will join the Total-Body PET Physics Group led by Dr Fabian Schmidt at the Department of Nuclear Medicine and Clinical Molecular Imaging & Werner Siemens Imaging Center at the University Hospital Tübingen, the first university hospital in Germany to install a Siemens Biograph Vision Quadra LAFOV PET/CT. The project spans PET physics, advanced computation and validation in clinical Total-Body PET datasets.
The successful candidate will collaborate closely with leading European academic and industrial partners, participate in international secondments and contribute to the translation of novel quantitative PET methodologies into clinical applications. Research is performed on the Siemens Biograph Vision Quadra, the first long-axial field-of-view PET/CT installed at a German university hospital, providing access to state-of-the-art imaging infrastructure and unique clinical datasets.
