Internship PBK Modelling and High-Throughput NGRA of Environmental Compounds
We are looking for a motivated scientist to join our modelling team. You'll contribute to an exciting project, developing and applying physiologically based pharmacokinetic (PBPK) models using a high-throughput framework to support next-generation risk assessment (NGRA) of environmental chemicals (e.g. pesticides, environmental contaminants, food contact materials etc).
The internship is suited to a master student or early-career scientist with a strong interest in computational toxicology and toxicokinetics, in vitro to in vivo extrapolation (IVIVE) and the use of new approach methodologies (NAMs) in chemical safety assessment.
A key requirement for this role is good working knowledge of R programming language. You will work with an existing high-throughput modelling and data-analysis pipeline developed in R, supporting its application to environmental compounds, by organizing input datasets, running pipeline components, checking outputs, generating summaries, and interpretating model results.
The intern may support activities such as:
We are looking for an organised, curious, and detail-oriented candidate with a strong interest in computational approaches to chemical safety assessment.
The candidate should have:
MSc in toxicology, pharmacology, environmental science, computational biology, or a related field (recently completed or about to complete)
A detail-oriented mindset and ability to work independently as well as in a team
Prior experience with PBK/PBPK modelling, IVIVE, toxicokinetics, or NGRA is a plus but not essential. Familiarity with packages or tools for modelling, data analysis, and visualisation in R is most important.
Candidates must currently reside in the EU or the UK and possess a valid work authorization for the country in which they will be employed.
What's in store for you
The dynamic team behind ESQlabs unites people with different backgrounds, spanning disciplines like pharmaceutical sciences, physics, bioinformatics, mathematics, data science, and software engineering. Our trust in each other, our open-mindedness, and our constant quest for excellence and innovation unite us. We value flat hierarchies, where everyone can contribute ideas and expertise to develop the best product. We are passionate, always willing to broaden our horizons, and love our start-up culture.
You will also benefit from:
About us
We collaborate with global corporations in the pharma and chemical industry, as well as start-ups in the life-science technology sector and academic and non-profit research institutions. We define new standards in pharmacometrics and systems pharmacology and toxicology areas. Our software and model platforms help scientists understand mechanisms of diseases and chemical toxicity to optimize individualized treatment of patients and protect the health of the animal and human life.
ESQlabs has attracted international players as sponsors for the OSP Software development. In addition, funding through national and EU-wide research grants allows us to develop our core technologies continuously.
For more information about our culture, values and benefits visit our Unique career opportunities - ESQlabs GmbH.
At ESQlabs, we are committed to diverse backgrounds and experiences.
