5 beste Stellen als in immunology in nürnberg – aktuell auf Personalsuche

Universitätsklinikum Erlangen
Mikrobiologisches Institut – Klinische Mikrobiologie, Immunologie und Hygiene
Prof. Dr. rer. nat. Sven Krappmann
Wasserturmstr. 3/5
91054 Erlangen

Ansprechperson bei Fragen
Prof. Dr. rer. nat. Sven Krappmann
Molecular Mycology Group leader
+49 (0)9131 85 – 32580

PhD Postition Mycology / Immunology (f/m/d)

Veröffentlicht seit: 21.07.2026
Job-Nr.: 13306

Ansprechperson bei Fragen

Prof. Dr. rer. nat. Sven Krappmann
Molecular Mycology Group leader
+49 (0)9131 85 – 32580

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Universitätsklinikum Erlangen
Mikrobiologisches Institut – Klinische Mikrobiologie, Immunologie und Hygiene
Prof. Dr. rer. nat. Sven Krappmann
Wasserturmstr. 3/5
91054 Erlangen

PhD Postition Mycology / Immunology (f/m/d)
Veröffentlicht seit: 21.07.2026
Job-Nr.: 13306

Universitätsklinikum Erlangen
Mikrobiologisches Institut – Klinische Mikrobiologie, Immunologie und Hygiene
Prof. Dr. rer. nat. Sven Krappmann
Wasserturmstr. 3/5
91054 Erlangen

Ansprechperson bei Fragen
Prof. Dr. rer. nat. Sven Krappmann
Molecular Mycology Group leader
+49 (0)9131 85 – 32580

Klingt spannend?
Das sind wir:

The Molecular Mycology research group hosted by Prof. Dr. rer. nat. Sven Krappmann at the Institute of Clinical Microbiology, Immunology and Hygiene of the University Hospital Erlangen offers a PhD position to investigate the interaction of Aspergillus fumigatus with eosinophils in a model of allergic lung inflammation.

Research activities of the lab are directed at determinants of fungal virulence with a focus on the opportunistic pathogen Aspergillus fumigatus. This environmental mould is able to cause a variety of infectious diseases, such as allergic bronchopulmonary aspergillosis (ABPA).

In close collaboration with the Department of Infection Biology headed by Prof. David Vöhringer, we have investigated the role of eosinophilic granulocytes in the course of ABPA as well as fungal determinants of pathology. For this purpose, timely research approaches and methodologies of immunology, microbiology, and molecular infection biology are followed.

Relevant publications

Dietschmann et al. (2022) Phosphatidylinositol 3-kinase (PI3K) orchestrates Aspergillus fumigatus-induced eosinophil activation independently of canonical Toll-like receptor (TLR)/C-type-lectin receptor (CLR) signaling. mBio 13: e0123922.
Adam et al. (2025) Signaling events driving Aspergillus fumigatus-induced eosinophil activation. Int J Med Microbiol 318: 151641.
Graf et al. (2026) IL-33 expressing cDC2s promote expansion of ILC2s and eosinophilia in fungal airway inflammation in male mice. bioRxiv, doi: 10.64898/2025.12.02.691763.

Your tasks:

This DFG-funded tandem project wants to shed light on the crosstalk between Aspergillus fumigatus and eosinophilic granulocytes in the context of allergic lung inflammation by fulfilling the following tasks:

Characterising transcription factors that shape the fungal transcriptome upon interaction with eosinophils
Investigating the relevance of extracellular proteolysis in this scenario

Experimental approaches and readouts include

Flow cytometry
Quantification of cytokine levels by ELISA etc.
RNAseq analyses
Generation of recombinant fungal strains
Genotyping and phenotyping of A. fumigatus mutants

Comments:

Applications must comprise the ususal documents such as a convincing statement of motivation, scientific CV with competences, referencing letters, copies of transcript records, and certificates (high school diploma, Bachelor and Master study results).

Essential experience/qualifications:

Intrinsic curiosity for fundamental insights in fungal immunity
Strong motivation to conduct research as a team player
Competences in relevant experimental approaches
Urge to accomplish research tasks in an autonomous and interdisciplinary manner
Routine in cell culture techniques
Sound immunological knowledge

Additionally beneficial are:

Hands-on experience with methodologies of fungal research
Competences in working with filamentous fungi

We offer:

Position will be paid according to the German salary scale (TV-L)
Attractive PhD thesis project in highly relevant research area at the intersection of Mycology and Immunology
Stimulating research environment at the Microbiological Institute
Membership in the structured educational PhD program of the Life@FAU Graduate School
Option to become associated to the DFG-funded ImmunoMicroTope Research Training Group 2740
Thorough and qualified introduction to the research project and supportive working group
Fixed-term contract for up to 36 months

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Wir zählen zu den besten Krankenhäusern Deutschlands und sind einer der größten Arbeitgeber in Mittelfranken. Diesen Erfolg erarbeiten tagtäglich unsere über 10.000 hoch qualifizierten Beschäftigten in unterschiedlichsten Berufen. Wir als Uniklinikum Erlangen wissen, dass alle unsere Beschäftigten wichtig sind, damit auch in Zukunft modernste Medizin, ausgezeichnete Forschung und Patientenversorgung auf höchstem Niveau gelingen.

Wenn Sie sich eine Tätigkeit mit einem hohen sozialen Wert wünschen und die Welt der Spitzenmedizin mit uns gemeinsam gestalten und ermöglichen möchten, dann sind Sie bei uns richtig!

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