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Post doc (all genders) in liver immunity - section Regenerative Medicine and Immunology

UKE - Universitätsklinikum Hamburg-Eppendorf -
Hamburg

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Details zur Stelle

Teilzeit | Vollzeit | Befristeter Vertrag
63.600 € – 91.100 € pro Jahr
vor 13 Tagen

Leistungen

Jobticket
Kostenfreies oder vergünstigtes Deutschland-Ticket

Qualifikationen

Biologie
Doktorat

Vollständige Stellenbeschreibung

Better together. For life.

At the University Medical Center Hamburg-Eppendorf (UKE), we are committed to excellence in research, education, and comprehensive healthcare across our clinics. Every day, our team of approximately 16,100 dedicated employees works to make the world a healthier place. Our goal is to be one of the leading university hospitals while also being the best employer in our industry.

At UKE, we believe that meaningful and successful work should align with our employees' personal needs and individual lifestyles. Just as diverse as these needs are, so too is the variety of personalized solutions we offer.

Welcome to the UKE.

Post doc (all genders) in liver immunity - section Regenerative Medicine and Immunology

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Job-ID: J000006734
Contract Type: Temporary
Employment Type: Full time/ Part time
Closing Date: 07.09.2026
Organization: UKE_Zentrum für Innere Medizin
Category: Research & Science
Department: III. Med. Klinik

Main tasks

The liver is critical in mediating organismal homeostasis. Previous studies from our group have shown that early in life innate lymphoctes are enriched in human organs. More recent studies suggest that innate lymphocytes including NK cells are critical in editing immune cell populations in tissues and thereby can provide protection against autoimmunity. However, this may also have consequences for the control of viral infections. During the lifespan the immune system faces time-window dependent challenges characterized by changes in microbial and virus exposure and tissue growth, resulting in an increased risk of infectious and immune-mediated diseases early in life. Specifically, young children are more susceptible to chronic hepatitis B virus infection.

In this project, the consequences of interactions between innate lymphcoytes and lymphocytes of the adapative immune system in the liver are investigated in the context of liver inflammation and hepatitis B virus infection. The studies build on analyses of observational studies, including several single cell omics and computational analyses and innovative human tissue-based organoid systems to decipher the molecular interactions between immune cells as well as parenchymal cells in tissue (re) generation, HBV infection and inflammation.

The goal is to understand critical developmental programs regulating liver immune development and identify pathways that can be targeted to prevent chronic HBV infection.

Main tasks:

Experimental studies of liver organoid systems and liver immune cells, including planning of experimental design, experiments, documentation and statistical analysis of results; interpretation, discussion and presentation of results
Computational analyses of high dimensional data, including flow cytometry, scRNAseq and spatial transcriptomics
Scientific publishing, presentation at international conferences, communitty outreach

This position is temporary for 2 years due to third-party funding and starts on 1st of November 2026.

Your Profile

Completed university degree and preferably a PhD in biology, biochemistry, or a related field, or a medical degree with a clinical-scientific background
Training in (tissue) immunology or infectious diseases
Expertise in computational analyses of various OMICS data sets
2 letters of recommendation from former mentors
Strong interest in pursuing research in academia

We look much forward to receiving your application, including CV, publication list, and certificates recommendation letters.

Immunity status

Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.

Our Offer

Fair and transparent compensation in accordance with our collective bargaining agreement TVöD/VKA / TV-Ärzte/VKA (€ 63,600 – € 91,100), taking into account qualifications and professional experience. The salary range applies to a full-time position of 38.5 hours per week. The amounts listed are guidelines and do not constitute a salary guarantee.
Targeted and individualized professional development at both the technical and project levels is provided, offering long-term prospects in a meaningful work environment
Comprehensive continuing education and training programs at our UKE Academy for Education and Career
Opportunities to help shape our “UKE INside” personnel policy through cross-functional and cross-hierarchical projects
Sustainable commuting: Subsidies for the Deutschlandticket as a job ticket and Dr. Bike bicycle service
Excellent health, prevention, and sports programs
Family-friendly work environment: Partnerships for childcare, free vacation care, counseling for employees with family members requiring care
A secure job, meaningful work, and a supportive team environment
Structured onboarding and open knowledge sharing within the team
Our employee restaurant offers a wide variety of culinary options; additional options are available at the “Health Kitchen” cafés and bistros and at a supermarket located directly on the premises

Contact

Contact to the department

Prof. Dr. Bunders
- [email protected]
Recruiting contact

Recruiting Team
- +49 (0) 40 7410-52599

About us

We live diversity and value variety

We offer a work environment that provides equal opportunities regardless of age, gender, sexual identity, disability, ethnic and social origin, or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under-representation of one gender in the advertised area. Persons with severe disabilities with equal aptitude, competence, and professional performance will be given priority.

Apply NowApply online now via our career portal: https://uke.jobs/index.php?ac=application&jobad_id=6734

Employer

Erstes gesamtzertifiziertes Universitätsklinikum Deutschlands

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Post doc (all genders) in liver immunity - section Regenerative Medicine and Immunology

Main tasks

Your Profile

Immunity status

Our Offer

Contact

Contact to the department

Prof. Dr. Bunders

Recruiting contact

Recruiting Team

About us

Employer

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