The Fraunhofer Institute for Translational Medicine and Pharmacology ITMP in Berlin-Mitte focuses on the development of new and personalized treatment strategies for patients with rheumatic diseases. This new Fraunhofer site is being established in close collaboration with Charité – Universitätsmedizin Berlin.
Be part of change
You will work at the interface of bioinformatics, translational medicine, and experimental research. Our clinical and research teams conduct a broad range of innovative studies, including Investigator-Initiated Trials (IITs), with the goal of developing novel therapeutic approaches for rheumatic diseases. These include, among others, the use of CAR T-cell therapies and therapeutic antibodies to reprogram the immune system.
In addition, we perform large-scale multi-omics analyses of patient cohorts to gain deeper insight into disease pathology. We also employ a range of disease models to investigate specific cellular and molecular mechanisms in detail.
In this role, you will support the analysis of ongoing experimental datasets while advancing innovative approaches for the integration and interpretation of complex, multidimensional data.
Your responsibilities will include in particular:
- Performing computational analyses of high-throughput sequencing datasets, including:
- single-cell RNA-seq and ATAC-seq
- spatial transcriptomics / spatial multi-omics
- bulk RNA-seq and ATAC-seq
- CUT&RUN
- Developing, implementing, and optimizing bioinformatics pipelines for data processing and analysis
- Integrating multi-omics datasets with clinical and patient-related data
- Contributing to the development of novel computational approaches for combining large-scale datasets
- Collaborating closely with laboratory scientists, clinicians, and fellow bioinformaticians
- Interpreting and presenting results to multidisciplinary teams
- Ensuring reproducibility, proper documentation, and sound data management practices
What you contribute
- A completed PhD in biology, bioinformatics, biomedicine, or a related life science discipline
- Strong hands-on experience in bioinformatics
- Excellent programming skills in R and Python
- Proven experience in the analysis of next-generation sequencing (NGS) data
- Practical experience in several of the following areas:
- single-cell transcriptomics
- epigenomics, e.g. ATAC-seq, CUT&RUN, ChIP-seq
- spatial transcriptomics or multi-omics
- Experience handling large-scale datasets and working in high-performance computing environments
- Solid knowledge of statistical methods for the analysis of high-dimensional data
- Experience with integrative analysis across multiple data modalities
- Strong problem-solving skills and the ability to work independently
- Fluency in German and English
What we offer
- A dynamic and interdisciplinary research environment
- A modern research facility with access to cutting-edge technologies
- Diverse and challenging tasks with high scientific relevance
- Close collaboration with partners in academic medicine and translational research
- An attractive workplace in the heart of Berlin
- A good work-life balance through flexible working hours and a flexitime model
- 30 days of annual leave per year, as well as December 24 and December 31 off
- An occupational pension scheme (VBL) and other public-sector social benefits, including an annual special payment
- Capital-forming benefits
- A subsidy for the Deutschlandticket as a job ticket
- Opportunities for personal and professional development through a broad range of training programs
- Corporate benefits with attractive offers from well-known brands and manufacturers
- Access to Fraunhofer’s extensive professional and scientific network
The weekly working time is 39 hours. The position is initially limited until December 31, 2027, and can also be filled on a part-time basis. We value and promote the diversity of our employees' skills and therefore welcome all applications – regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, sexual orientation and identity. Severely disabled persons are given preference in the event of equal suitability. Our tasks are diverse and adaptable – for applicants with disabilities, we work together to find solutions that best promote their abilities. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD).
With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.
Ready for a change? Then apply now and make a difference! Once we have received your online application, you will receive an automatic confirmation of receipt. We will then get back to you as soon as possible and let you know what happens next.
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Requisition Number: 85031 Application Deadline:
